Identification of Highly Potent & Selective VAV1 Molecular Glue Degrader HC118
- Exploring how VAV1 is an emerging first in class target for autoimmune and chronic inflammatory indications
- Outlining how HC118 is an orally available molecular glue degrader that is highly potent and selective targeting VAV1
- Discovering how HC118 is highly efficacious in multiple animal models and demonstrated good preclinical safety profile